Establishing a prognostic model with ferroptosis-related long non-coding RNAs in bladder cancer.

ABSTRACT:

Background

Ferroptosis is a distinct form of cell death that has the potential to supersede the drug resistance that is commonly observed with current chemotherapeutic agents. As a result, ferroptosis presents a new and innovative therapeutic pathway for cancer treatment. The current understanding regarding the expression of genes associated with ferroptosis in bladder cancer (BLCA) and their prognostic implications remains unclear. Consequently, this study aimed to examine the potential prognostic value of ferroptosis-associated long non-coding RNAs (lncRNAs) in BLCA.

Methods

The Cancer Genome Atlas (TCGA) was accessed to download RNA sequencing data and clinicopathological features of BLCA while accessing the FerrDb database to download ferroptosis-associated genes. The st

SUBMITTER: Li W 

PROVIDER: S-EPMC10493782 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature