Challenges in anti-aging medicine-trends in biomarker discovery and therapeutic interventions for a healthy lifespan.

ABSTRACT: We are facing a growing aging population, along with increasing pressure on health systems, caused by the impact of chronic co-morbidities (i.e. cancer, cardiovascular and neurodegenerative diseases) and functional disabilities as people age. Relatively simple preventive lifestyle interventions, such as dietary restriction and physical exercise, are important contributors to active and healthy aging in the general population. However, as shown in model organisms or in 'in vitro' conditions, lifestyle-independent interventions may have additional health benefits and can even be conceived as possible reversers of the aging process. Thus, pharmaceutical laboratories, research institutes, and universities are putting more and more effort into finding new molecular pathways and druggable target

SUBMITTER: Popescu I 

PROVIDER: S-EPMC10494298 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature