Impact factors of Blastocystis hominis infection in persons living with human immunodeficiency virus: a large-scale, multi-center observational study from China.

ABSTRACT:

Background

Blastocystis hominis (Bh) is zoonotic parasitic pathogen with a high prevalent globally, causing opportunistic infections and diarrhea disease. Human immunodeficiency virus (HIV) infection disrupts the immune system by depleting CD4⁺ T lymphocyte (CD4⁺ T) cell counts, thereby increasing Bh infection risk among persons living with HIV (PLWH). However, the precise association between Bh infection risk and HIV-related biological markers and treatment processes remains poorly understood. Hence, the purpose of the study was to explore the association between Bh infection risk and CD4⁺ T cell counts, HIV viral load (VL), and duration of interruption in antiviral therapy among PLWH.

Methods

A large-scale multi-center cross-sectional study

SUBMITTER: Zhang SX 

PROVIDER: S-EPMC10494452 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature