Ontology highlight
ABSTRACT:
SUBMITTER: Jamshidnejad-Tosaramandani T
PROVIDER: S-EPMC10494546 | biostudies-literature | 2023
REPOSITORIES: biostudies-literature
Jamshidnejad-Tosaramandani Tahereh T Kashanian Soheila S Karimi Isaac I Schiöth Helgi B HB
Frontiers in pharmacology 20230828
Intranasal administration is a drug delivery approach to provide a non-invasive pharmacological response in the central nervous system with relatively small peripheral side effects. To improve the residence time of intranasal drug delivery systems in the nasal mucosa, mucoadhesive polymers (e.g., chitosan) can be used. Here, insulin-loaded chitosan nanoparticles were synthesized and their physiochemical properties were evaluated based on requirements of intranasal administration. The nanoparticl ...[more]