Construction of a prediction model for prognosis of bladder cancer based on the expression of ion channel-related genes.

ABSTRACT:

Objectives

To construct a prediction model for the prognosis of bladder cancer patients based on the expression of ion channel-related genes (ICRGs).

Methods

ICRGs were obtained from the existing researches. The clinical information and the expression of ICRGs mRNA in breast cancer patients were obtained from the Cancer Genome Atlas database. Cox regression analysis, minimum absolute shrinkage and selection operator regression analysis were used to screen breast cancer prognosis related genes, which were verified by immunohistochemistry and qRT-PCR. The risk scoring equation for predicting the prognosis of patients with bladder cancer was constructed, and the patients were divided into high-risk group and low-risk group according to the median risk score. Immune cell infiltr

SUBMITTER: Zhang D 

PROVIDER: S-EPMC10495249 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature