A proper protocol for routine ¹⁸F-FDG uEXPLORER total-body PET/CT scans.

ABSTRACT:

Background

Conventional clinical PET scanners typically have an axial field of view (AFOV) of 15-30 cm, resulting in limited coverage and relatively low photon detection efficiency. Taking advantage of the development of long-axial PET/CT, the uEXPLORER PET/CT scanner with an axial coverage of 194 cm increases the effective count rate by approximately 40 times compared to that of conventional PET scanners. Ordered subset expectation maximization (OSEM) is the most widely used iterative algorithm in PET. The major drawback of OSEM is that the iteration process must be stopped before convergence to avoid image degradation due to excessive noise. A new Bayesian penalized-likelihood iterative PET reconstruction, named HYPER iterative, was developed and is now available on the uEXPLORER

SUBMITTER: Hu H 

PROVIDER: S-EPMC10495295 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature