Ontology highlight
ABSTRACT:
SUBMITTER: Pasquereau-Kotula E
PROVIDER: S-EPMC10495336 | biostudies-literature | 2023 Sep
REPOSITORIES: biostudies-literature
Pasquereau-Kotula Ewa E Nigro Giulia G Dingli Florent F Loew Damarys D Poullet Patrick P Xu Yi Y Kopetz Scott S Davis Jennifer J Peduto Lucie L Robbe-Masselot Catherine C Sansonetti Philippe P Trieu-Cuot Patrick P Dramsi Shaynoor S
Scientific reports 20230911 1
In this work, we investigated the oncogenic role of Streptococcus gallolyticus subsp. gallolyticus (SGG), a gut bacterium associated with colorectal cancer (CRC). We showed that SGG UCN34 accelerates colon tumor development in a chemically induced CRC murine model. Full proteome and phosphoproteome analysis of murine colons chronically colonized by SGG UCN34 revealed that 164 proteins and 725 phosphorylation sites were differentially regulated. Ingenuity Pathway Analysis (IPA) indicates a pro-tu ...[more]