Association of uric acid levels with severity of Plasmodium infections: a systematic review and meta-analysis.

ABSTRACT: Elevated uric acid (UA) levels have been reported in malaria patients and are particularly prominent in severe malaria cases. This study aims to synthesize the difference in UA levels between malaria patients and uninfected controls, and between patients with severe and non-severe malaria. A comprehensive literature search was carried out across databases such as Embase, MEDLINE, Ovid, PubMed, Scopus, ProQuest, and Google Scholar to identify relevant studies for inclusion. The methodological quality of the included studies was evaluated independently by two reviewers using the JBI critical appraisal tool for observational studies. A meta-analysis was performed to calculate the pooled effect sizes, expressed as Hedges' g, with 95% confidence intervals (CIs). The Hedges' g was pooled using t

SUBMITTER: Kuraeiad S 

PROVIDER: S-EPMC10495360 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature