Metabolic syndrome and cognitive deficits in the Greek cohort of Epirus Health Study.

ABSTRACT:

Background

Metabolic syndrome is considered an important risk factor for cognitive decline and dementia. However, the evidence in middle-aged individuals is still conflicting. The aim of the study was to explore the association between metabolic syndrome and its individual components with cognitive function and to investigate possible interaction between sex, age and genetic predisposition for metabolic syndrome and Alzheimer's disease in a middle-aged Greek cohort.

Methods

A total of 2,077 healthy adults (mean age: 46.7 years) were included in the primary cross-sectional analysis and 305 of them in secondary prospective analyses. Metabolic syndrome was defined by the revised National Cholesterol Education-Adult Treatment Panel III and the International Diabetes Federation c

SUBMITTER: Koutsonida M 

PROVIDER: S-EPMC10495510 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature