Increased interhemispheric functional connectivity during non-dominant hand movement in right-handed subjects.

ABSTRACT: Hand preference is one of the behavioral expressions of lateralization in the brain. Previous fMRI studies showed the activation in several regions including the motor cortex and the cerebellum during single-hand movement. However, functional connectivity related to hand preference has not been investigated. Here, we used the generalized psychophysiological interaction (gPPI) approach to investigate the alteration of functional connectivity during single-hand movement from the resting state in right-hand subjects. The functional connectivity in interhemispheric motor-related regions including the supplementary motor area, the precentral gyrus, and the cerebellum was significantly increased during non-dominant hand movement, while functional connectivity was not increased during dominant ha

SUBMITTER: Tsurugizawa T 

PROVIDER: S-EPMC10495657 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature