Kidney Function and Long-Term Risk of End-Stage Kidney Disease and Mortality in a Multiethnic Population.

ABSTRACT:

Introduction

Contemporary differences between South Asian and White ethnicities in the incidence of end-stage kidney disease (ESKD) and mortality are poorly described.

Methods

Data for all South Asian patients who had an estimated glomerular filtration rate (eGFR) measure after January 1, 2006, and 1 million randomly selected participants of other ethnicities were extracted from the Clinical Practice Research Datalink (CPRD). All participants were followed-up with from index date until ESKD, all-cause mortality, or end of study. All-cause mortality rate and ESKD incidence rate by age were described among Whites and South Asians, and adjusted hazard ratios (HRs) of these 2 outcomes by baseline eGFR estimated using Cox proportional hazard model.

Results

A total of 40,88

SUBMITTER: Ling S 

PROVIDER: S-EPMC10496088 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature