Automated Segmentation of the Mouse Body Language to Study Stimulus-Evoked Emotional Behaviors.

ABSTRACT: Understanding the neural basis of emotions is a critical step to uncover the biological substrates of neuropsychiatric disorders. To study this aspect in freely behaving mice, neuroscientists have relied on the observation of ethologically relevant bodily cues to infer the affective content of the subject, both in neutral conditions or in response to a stimulus. The best example of that is the widespread assessment of freezing in experiments testing both conditioned and unconditioned fear responses. While robust and powerful, these approaches come at a cost: they are usually confined within selected time windows, accounting for only a limited portion of the complexity of emotional fluctuation. Moreover, they often rely on visual inspection and subjective judgment, resulting in inconsistenc

SUBMITTER: Chelini G 

PROVIDER: S-EPMC10496135 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature