People who inject oral morphine favor experimentation with injectable opioid substitution.

ABSTRACT:

Background

The French Addictovigilance network has observed the existence of the intravenous use of oral morphine capsules among people suffering from opioid use disorders. According to persons who inject morphine, these capsules are easy to dissolve and then inject, giving them the image of an "injectable" opioid substitution treatment (OST). In France, validated OSTs are only available orally, so dissolving morphine capsules represents the only alternative for patients who are not sufficiently relieved by oral forms. This practice presents risks related to the potential persistence of particles of the oral galenic in the injectable solution, despite its filtration, but also risks-notably of overdose-related to the pharmacological effects of opioids and to variations of the quanti

SUBMITTER: Bertin C 

PROVIDER: S-EPMC10496178 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature