MiR-128-3p inhibits intramuscular adipocytes differentiation in chickens by downregulating FDPS.

ABSTRACT:

Background

Intramuscular fat (IMF) content is the major indicator for evaluating chicken meat quality due to its positive correlation with tenderness, juiciness, and flavor. An increasing number of studies are focusing on the functions of microRNAs (miRNAs) in intramuscular adipocyte differentiation. However, little is known about the association of miR-128-3p with intramuscular adipocyte differentiation. Our previous RNA-seq results indicated that miR-128-3p was differentially expressed at different periods in chicken intramuscular adipocytes, revealing a possible association with intramuscular adipogenesis. The purpose of this research was to investigate the biological functions and regulatory mechanism of miR-128-3p in chicken intramuscular adipogenesis.

Results

The resul

SUBMITTER: Zhu S 

PROVIDER: S-EPMC10496186 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature