Rinmaker: a fast, versatile and reliable tool to determine residue interaction networks in proteins.

ABSTRACT:

Background

Residue Interaction Networks (RINs) map the crystallographic description of a protein into a graph, where amino acids are represented as nodes and non-covalent bonds as edges. Determination and visualization of a protein as a RIN provides insights on the topological properties (and hence their related biological functions) of large proteins without dealing with the full complexity of the three-dimensional description, and hence it represents an invaluable tool of modern bioinformatics.

Results

We present RINmaker, a fast, flexible, and powerful tool for determining and visualizing RINs that include all standard non-covalent interactions. RINmaker is offered as a cross-platform and open source software that can be used either as a command-line tool or through a web

SUBMITTER: Spano A 

PROVIDER: S-EPMC10496328 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature