The course of health-related quality of life after the diagnosis of childhood cancer: a national cohort study.

ABSTRACT:

Background

Comprehensive insight in the longitudinal development of health-related quality of life (HRQOL) after childhood cancer diagnosis could improve quality of care. Thus, we aimed to study the course and biopsychosocial determinants of HRQOL in a unique national cohort of children with cancer.

Methods

HRQOL of 2154 children with cancer was longitudinally reported (median: 3 reports) between diagnosis and 5 years after, using the pediatric quality of life inventory generic core scales (PedsQL). HRQOL was modelled over time since diagnosis using mixed model analysis for children 2-7 years (caregiver-reports) and ≥ 8 years (self-reports). Differences in the course between hematological, solid and central nervous system malignancies were studied. Additional associations of

SUBMITTER: van Gorp M 

PROVIDER: S-EPMC10496372 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature