The effect of HIV infection, antiretroviral therapy on carotid intima-media thickness: A systematic review and meta-analysis.

ABSTRACT:

Aims

We performed a systematic review and meta-analysis on the effect of HIV infection and antiretroviral therapy (ART) on carotid intima-media thickness (cIMT) to elucidate the role of HIV infection and ART. Also, an analysis on the role of ethnicity and gender on cIMT in HIV-infected populations was performed.

Main methods

We searched the PubMed, Web of Science, the WHO websites and International AIDS Society for published observational studies were conducted by two independent reviewers for studies comparing HIV-infected antiretroviral-experienced patients and/or inexperienced with healthy controls on cIMT. The primary outcome was the standardized mean difference (SMD) of cIMT.

Findings

Twenty studies (five cohort, 15 cross-sectional, and two both cohort and cross-

SUBMITTER: Msoka TF 

PROVIDER: S-EPMC10496646 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature