Sequential multiple assignment randomised controlled trial protocol for developing an adaptive intervention to improve depressive symptoms among family caregivers of people with dementia.

ABSTRACT:

Objectives

Family caregivers of people with dementia (FC-of-PWD) suffer from a high level of stress and depressive symptoms, which usually require different interventions at different stages. Although some standalone interventions such as behavioural activation (BA) and mindfulness practice (MP) have been shown to be potentially effective at reducing depressive symptoms, the best sequence and combination of these interventions for caregivers are unknown. This study aims to develop and identify a two-stage adaptive intervention with prespecified rules guiding whether, how or when to offer different interventions initially/over time to reduce depressive symptoms in FG-of-PWD.

Methods

A sequential multiple assignment randomised trial design will be adopted. 272 FG-of-PWD with m

SUBMITTER: Kor PPK 

PROVIDER: S-EPMC10496708 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature