Challenges in Therapeutic Drug Monitoring: Optimizing Biological Treatments in Patients With Inflammatory Bowel Disease and Other Immune-Mediated Inflammatory Diseases.

ABSTRACT:

Background

Therapeutic drug monitoring (TDM) is a decision-making tool for optimizing the use of certain therapies. In this article, the authors review the role of proactive TDM of biological agents in patients with inflammatory bowel disease (IBD) and other immune-mediated inflammatory diseases (IMID). They also discuss the future of TDM as a component of personalized medicine from the clinical laboratory perspective.

Methods

This narrative review originated from proceedings of the fifth biannual Challenges in Therapeutic Drug Monitoring seminar and was supplemented by additional literature identified at various stages of critical review.

Results

Proactive TDM aims to achieve adequate concentrations of biological drugs, such that patients attain and maintain an optim

SUBMITTER: Papamichael K 

PROVIDER: S-EPMC10497208 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature