When the available blood supply mismatches the needs of the patient.

ABSTRACT:

Background

Substantial regional differences in the genetic patterns related to blood group have been observed across different continents. This diversity means that the blood supply, as an essential part of patient care, is increasingly impacted by global migration. Consequently, the Austrian blood donor population does not match the immigrant patient population. This mismatch is likely to result in the formation of alloantibodies to red cell antigens in the chronically transfused. Subsequently, major difficulties in providing compatible blood emerge.

Material and methods

The study included patients of African origin (n=290) and Caucasians who represent the Austrian donor population (n=1,017). Genetic typing was performed for up to 69 blood group polymorphisms with a multipl

SUBMITTER: Weidner L 

PROVIDER: S-EPMC10497382 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature