Arabidopsis flippase ALA3 is required for adjustment of early subcellular trafficking in plant response to osmotic stress.

ABSTRACT: To compensate for their sessile lifestyle, plants developed several responses to exogenous changes. One of the previously investigated and not yet fully understood adaptations occurs at the level of early subcellular trafficking, which needs to be rapidly adjusted to maintain cellular homeostasis and membrane integrity under osmotic stress conditions. To form a vesicle, the membrane needs to be deformed, which is ensured by multiple factors, including the activity of specific membrane proteins, such as flippases from the family of P4-ATPases. The membrane pumps actively translocate phospholipids from the exoplasmic/luminal to the cytoplasmic membrane leaflet to generate curvature, which might be coupled with recruitment of proteins involved in vesicle formation at specific sites of the don

SUBMITTER: Pukysova V 

PROVIDER: S-EPMC10498020 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature