Accelerometer-derived sleep measures in idiopathic dystonia: A UK Biobank cohort study.

ABSTRACT:

Background

Sleep disturbance is an increasingly recognized non-motor trait in dystonia, with varying findings reported to date. Here, we examine sleep in a UK Biobank derived dystonia cohort using subjective self-reported sleep symptoms and objective accelerometer-derived sleep measures, with comparison to a control population.

Methods

A total of 241 dystonia cases were compared to 964 matched controls in analysis of self-reported sleep symptoms and changes in sleep architecture using wrist-worn triaxial accelerometers.

Results

Dystonia participants had poorer self-reported sleep patterns compared to controls. Accelerometery measurements demonstrated later sleep times, reduced time in bed, and shifts in circadian rhythm. No association was observed with pain, and only

SUBMITTER: Bailey GA 

PROVIDER: S-EPMC10498055 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature