Genome-wide association and replication studies for handedness in a Korean community-based cohort.

ABSTRACT:

Introduction

Handedness is a conspicuous characteristic in human behavior, with a worldwide proportion of approximately 90% of people preferring to use the right hand for many tasks. In the Korean population, the proportion of left-handedness is relatively low at approximately 7%-10%, similar to that in other East-Asian cultures in which the use of the left hand for writing and other public activities has historically been oppressed.

Methods

In this study, we conducted two genome-wide association studies (GWASs) between right-handedness and left-handedness, and between right-handedness and ambidexterity using logistic regression analyses using a Korean community-based cohort. We also performed association analyses with previously reported variants and our findings.

Result

SUBMITTER: Song Y 

PROVIDER: S-EPMC10498080 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature