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Genome assembly and annotation of the Sharp-nosed Pit Viper Deinagkistrodon acutus based on next-generation sequencing data.


ABSTRACT: The study of the currently known >3,000 species of snakes can provide valuable insights into the evolution of their genomes. Deinagkistrodon acutus, also known as Sharp-nosed Pit Viper, one hundred-pacer viper or five-pacer viper, is a venomous snake with significant economic, medicinal and scientific importance. Widely distributed in southeastern China and South-East Asia, D. acutus has been primarily studied for its venom. Here, we employed next-generation sequencing to assemble and annotate a highly continuous genome of D. acutus. The genome size is 1.46 Gb; its scaffold N50 length is 6.21 Mb, the repeat content is 42.81%, and 24,402 functional genes were annotated. This study helps to further understand and utilize D. acutus and its venom at the genetic level.

SUBMITTER: Wang X 

PROVIDER: S-EPMC10498098 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature

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Genome assembly and annotation of the Sharp-nosed Pit Viper <i>Deinagkistrodon acutus</i> based on next-generation sequencing data.

Wang Xinyu X   Liu Lirong L   Zhu Wenbiao W   Wang Shiqing S   Shi Minhui M   Yang Shuhui S   Lu Haorong H   Cao Jun J  

GigaByte (Hong Kong, China) 20230904


The study of the currently known >3,000 species of snakes can provide valuable insights into the evolution of their genomes. <i>Deinagkistrodon acutus</i>, also known as Sharp-nosed Pit Viper, one hundred-pacer viper or five-pacer viper, is a venomous snake with significant economic, medicinal and scientific importance. Widely distributed in southeastern China and South-East Asia, <i>D. acutus</i> has been primarily studied for its venom. Here, we employed next-generation sequencing to assemble  ...[more]

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