[Risk factors for cancer-related cognitive impairment in breast and colorectal cancer patients who undergo chemotherapy].

ABSTRACT:

Background

Our study aims to evaluate the impact of different factors on cancer-related cognitive impairment in patients who undergo chemotherapy.

Methodology

Prospective longitudinal single-centre study that included patients with breast and colon carcinoma who underwent chemotherapy as part of their treatment. Clinical and genetic characteristics of the patients (single nucleotide polymorphisms, SNPs) were collected. Patients' neurocognitive status was assessed using eleven validated tests at three time points: before chemotherapy (M0 - baseline), between one and four weeks after completing chemotherapy (M1), and between 24-30 weeks after completing chemotherapy (M2).

Results

Sixty-two patients were included in this study; 82% were female, median age was 56 years (r

SUBMITTER: Iranzo P 

PROVIDER: S-EPMC10498134 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature