Automated contouring and statistical process control for plan quality in a breast clinical trial.

ABSTRACT:

Background and purpose

Automatic review of breast plan quality for clinical trials is time-consuming and has some unique challenges due to the lack of target contours for some planning techniques. We propose using an auto-contouring model and statistical process control to independently assess planning consistency in retrospective data from a breast radiotherapy clinical trial.

Materials and methods

A deep learning auto-contouring model was created and tested quantitatively and qualitatively on 104 post-lumpectomy patients' computed tomography images (nnUNet; train/test: 80/20). The auto-contouring model was then applied to 127 patients enrolled in a clinical trial. Statistical process control was used to assess the consistency of the mean dose to auto-contours between plans

SUBMITTER: Baroudi H 

PROVIDER: S-EPMC10498301 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature