Blood Levels of Organochlorine Contaminants Mixtures and Cardiovascular Disease.

ABSTRACT:

Importance

Cardiovascular toxic effects derived from high exposures to individual organochlorine compounds are well documented. However, there is no evidence on low but continuous exposure to combined organochlorine compounds in the general population.

Objective

To evaluate the association of combined exposure to several organochlorine compounds, including organochlorine pesticides and polychlorinated biphenyls, with incident cardiovascular disease (CVD) in the general population.

Design, setting, and participants

This prospective nested case-control study included data from 2 cohorts: the Swedish Mammography Cohort-Clinical (SMC-C) and the Cohort of 60-Year-Olds (60YO), with matched case-control pairs based on age, sex, and sample date. Baseline blood sampling occurr

SUBMITTER: Donat-Vargas C 

PROVIDER: S-EPMC10498337 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature