Association between retinol binding protein-4 and psoriasis vulgaris: a systematic review and meta-analysis.

ABSTRACT:

Background

Psoriasis vulgaris is a chronic skin disease which is related to cardiovascular and metabolic diseases. In the pathogenesis of these diseases, adipokines, including retinol binding protein-4 (RBP-4), play crucial roles. Studies have also shown that RBP-4 might be a meaningful factor in psoriasis however, relying on the analysis of a single study have some drawbacks.

Objective

To evaluate the association between RBP-4 and psoriasis vulgaris more comprehensively.

Methods

Six databases were searched to obtain relevant publications. The selection of the included studies was based on a criteria. The standardized mean difference (SMD) was used for analysis. A value of p < 0.05 was defined as significance.

Results

Seven studies were included, with 27

SUBMITTER: Gao G 

PROVIDER: S-EPMC10498455 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature