Functional connectivity in a monetary and social incentive delay task in medicated patients with schizophrenia.

ABSTRACT:

Introduction

Numerous studies indicate impaired reward-related learning in individuals with schizophrenia, with various factors such as illness duration, medication, disease severity, and level of analysis (behavioral or neurophysiological data) potentially confounding the results. Patients with schizophrenia who are treated with second-generation antipsychotics have been found to have a less affected reward system. However, this finding does not explain the neural dysfunctions observed in previous studies. This study aimed to address the open question of whether the less impaired reward-related behavior is associated with unimpaired task-related functional connectivity or altered task-related functional connectivity.

Methods

The study included 23 participants diagnosed with

SUBMITTER: Hanewald B 

PROVIDER: S-EPMC10498543 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature