Drug-Eluting-Balloon Angioplasty in Tunisian population versus Everolimus-platinum-chrome-stent for de-novo coronary lesion.

ABSTRACT:

Research problem

Drug-eluting balloon (DEB) angioplasty is a well-established treatment modality for in-stent restenosis, however its safety and efficacy in de-novo lesion especially in large vessel remains undetermined. Theoretically, DEB sight to eliminate stent thrombosis and reduce restenosis rates by leaving no metal behind.

Aim

To compare the results of angioplasty of de novo lesions by DEB (SEQUENT PLEASE) versus DES (Promus Premier and Promus Elite) in a Tunisian population. THE ENDPOINTS will be primarily the Late Lumen Loss at 12 months and secondarily the Major Cardiovascular Event rate (MACE) at 12 months.

Investigative process

This is a randomized controlled non-inferiority trial including 290 patients with chronic coronary disease or non-ST elevation myo

SUBMITTER: Hajlaoui N 

PROVIDER: S-EPMC10498760 | biostudies-literature | 2022 Decembre

REPOSITORIES: biostudies-literature