Reassessing the survival benefit of deceased donor liver transplantation - retrospective cohort study.

ABSTRACT:

Introduction

Currently in the United States, deceased donor liver transplant (DDLT) allocation priority is based on the Model for End-Stage Liver Disease including sodium (MELD-Na) score. The United Network for Organ Sharing's "Share-15" policy states that candidates with MELD-Na scores of 15 or greater have priority to receive local organ offers compared to candidates with lower MELD-Na scores. Since the inception of this policy, major changes in the primary etiologies of end-stage liver disease have occurred and previous assumptions need to be recalibrated.

Methods

We retrospectively analyzed the Scientific Registry of Transplant Recipients database between 2012 and 2021 to determine life years saved by DDLT at each interval of MELD-Na score and the time-to-equal risk and

SUBMITTER: Malamon JS 

PROVIDER: S-EPMC10498891 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature