Newly identified lineages of porcine hemagglutinating encephalomyelitis virus exhibit respiratory phenotype.

ABSTRACT: Swine pathogens have a long history of zoonotic transmission to humans, occasionally leading to sustained outbreaks or pandemics. Through a retrospective epidemiological study of swine populations in China, we describe novel lineages of porcine hemagglutinating encephalomyelitis virus (PHEV) complex coronaviruses (CoVs) that cause exclusively respiratory symptoms with no signs of the neurological symptoms typically associated with classical PHEV infection. Through large-scale epidemiological surveillance, we show that these novel lineages have circulated in at least eight provinces in southeastern China. Phylogenetic and recombination analyses of twenty-four genomes identified two major viral lineages causing respiratory symptoms with extensive recombination within them, between them, and

SUBMITTER: He WT 

PROVIDER: S-EPMC10499004 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature