Matrisome AnalyzeR - a suite of tools to annotate and quantify ECM molecules in big datasets across organisms.

ABSTRACT: The extracellular matrix (ECM) is a complex meshwork of proteins that forms the scaffold of all tissues in multicellular organisms. It plays crucial roles in all aspects of life - from orchestrating cell migration during development, to supporting tissue repair. It also plays critical roles in the etiology or progression of diseases. To study this compartment, we have previously defined the compendium of all genes encoding ECM and ECM-associated proteins for multiple organisms. We termed this compendium the 'matrisome' and further classified matrisome components into different structural or functional categories. This nomenclature is now largely adopted by the research community to annotate '-omics' datasets and has contributed to advance both fundamental and translational ECM research. He

SUBMITTER: Petrov PB 

PROVIDER: S-EPMC10499032 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature