Does the Addition of Mutations of CTNNB1 S45F to Clinical Factors Allow Prediction of Local Recurrence in Patients With a Desmoid Tumor? A Local Recurrence Risk Model.

ABSTRACT:

Background

The initial approach to the treatment of desmoid tumors has changed from surgical resection to watchful waiting. However, surgery is still sometimes considered for some patients, and it is likely that a few patients would benefit from tumor removal if the likelihood of local recurrence could be predicted. However, to our knowledge, there is no tool that can provide guidance on this for clinicians at the point of care.

Question/purpose

We sought to explore whether a combined molecular and clinical prognostic model for relapse in patients with desmoid tumors treated with surgery would allow us to identify patients who might do well with surgical excision.

Methods

This was a retrospective, single-center study of 107 patients with desmoid tumors who were surgic

SUBMITTER: Pinto FFE 

PROVIDER: S-EPMC10499079 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature