Prolactin does not seem to mediate the improvement on insulin resistance markers and blood glucose levels related to breastfeeding.

ABSTRACT:

Introduction

The prevalence of type 2 diabetes mellitus (T2DM) is increasing worldwide. Strategies to decrease this risk should be strongly encouraged. Lactation has been associated, for the mother, with reduction in future T2DM risk in several studies. The mechanisms behind this phenomenon, however, are poorly understood. The aims of this study were, first, to compare blood glucose levels and markers of insulin resistance (MIR) in early postpartum women with overweight/obesity according to their breastfeeding status and, second, to evaluate whether prolactin (PRL) levels could mediate improvements in these parameters.

Methods

The prospective study followed 95 women older than 18 years from early pregnancy for up to 60 to 180 days postpartum. All participants had a BMI > 25

SUBMITTER: de Oliveira JM 

PROVIDER: S-EPMC10499379 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature