Metabolomic and microbiomic insights into color changes during the sweating process in Dipsacus asper.

ABSTRACT: Sweating is one of the most important primary processing methods of Chinese medicinal materials. Dipsacus asper is a typical representative of sweating treatment that is recommended by the Chinese Pharmacopoeia. The color change of the fracture surface of the root is the prominent feature of sweating treatment. However, few studies have focused on the mechanism of color change during sweating treatment. In this study, widely targeted metabolomics and ITS high-throughput sequencing technologies were applied to detect metabolites and microbial structure and diversity in the root of D. asper during sweating treatment. A total of 667 metabolites, including 36 downregulated and 78 upregulated metabolites, were identified in D. asper following sweating treatment. The signifi

SUBMITTER: He H 

PROVIDER: S-EPMC10499524 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature