Long-term exercise training and inflammatory biomarkers in healthy subjects: a meta-analysis of randomized controlled trials.

ABSTRACT:

Objective

This meta-analysis investigated the effect of long-term exercise training (ET) including aerobic, resistance, and multicomponent ET on the levels of inflammatory biomarkers in randomized controlled trials (RCTs) involving healthy subjects.

Methods

We searched seven databases for articles until May 1st, 2023. A random-effect meta-analysis, subgroup analysis, meta-regressions as well as trim and fill method were conducted using STATA 16.0.

Result

Thirty-eight studies were included in the meta-analysis, involving 2,557 healthy subjects (mean age varies from 21 to 86 years). Long-term ET induced significantly decreased in the levels of interleukin-6 (IL-6) (SMD -0.16, 95% CI -0.30 to -0.03, p = 0.017), C-reactive protein (CRP) (SMD -0.18, 95% CI -0.31 to

SUBMITTER: Wang YH 

PROVIDER: S-EPMC10499556 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature