Resolution of Cerebral Inflammation Following Subarachnoid Hemorrhage.

ABSTRACT:

Background

Aneurismal subarachnoid hemorrhage (SAH) is a type of hemorrhagic stroke that, despite improvement through therapeutic interventions, remains a devastating cerebrovascular disorder that has a high mortality rate and causes long-term disability. Cerebral inflammation after SAH is promoted through microglial accumulation and phagocytosis. Furthermore, proinflammatory cytokine release and neuronal cell death play key roles in the development of brain injury. The termination of these inflammation processes and restoration of tissue homeostasis are of utmost importance regarding the possible chronicity of cerebral inflammation and the improvement of the clinical outcome for affected patients post SAH. Thus, we evaluated the inflammatory resolution phase post SAH and considere

SUBMITTER: Patsouris V 

PROVIDER: S-EPMC10499726 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature