Short-term triphenyltin exposure alters microbial homeostasis in the silkworm (Bombyx mori) midgut.

ABSTRACT: Triphenyltin (TPT) is a widespread synthetic chemical used in many fields and its potential risk to organisms has been comprehensively investigated using different animal models and species. Currently, little is known about the effects of TPT exposure on microbial midgut diversity, therefore we explored these effects in the lepidopterous silkworm model using 16S rDNA sequencing. In total, 5273 and 5065 operational taxonomic units (OTUs) were identified in control and TPT-exposure group samples, ranging from 424 to 728 OTUs/sample. Alpha-diversity analyses revealed that TPT exposure induced the fluctuations of gut microbial diversity and abundance while beta-diversity analyses identified a distinct impact on major gut microbiota components. In our microbiome analyses, 23 phyla and 353 gener

SUBMITTER: Zhou W 

PROVIDER: S-EPMC10499869 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature