Variation in spatial dependencies across the cortical mantle discriminates the functional behaviour of primary and association cortex.

ABSTRACT: Recent theories of cortical organisation suggest features of function emerge from the spatial arrangement of brain regions. For example, association cortex is located furthest from systems involved in action and perception. Association cortex is also 'interdigitated' with adjacent regions having different patterns of functional connectivity. It is assumed that topographic properties, such as distance between regions, constrains their functions, however, we lack a formal description of how this occurs. Here we use variograms, a quantification of spatial autocorrelation, to profile how function changes with the distance between cortical regions. We find function changes with distance more gradually within sensory-motor cortex than association cortex. Importantly, systems within the same type

SUBMITTER: Leech R 

PROVIDER: S-EPMC10499916 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature