Altered static and dynamic intrinsic brain activity in unilateral sudden sensorineural hearing loss.

ABSTRACT:

Introduction

Sudden sensorineural hearing loss (SSHL) is a critical otologic emergency characterized by a rapid decline of at least 30 dB across three consecutive frequencies in the pure-tone audiogram within a 72-hour period. This audiological condition has been associated with alterations in brain cortical and subcortical structures, as well as changes in brain functional activities involving multiple networks. However, the extent of cerebral intrinsic brain activity disruption in SSHL remains poorly understood. The aimed of this study is to investigate intrinsic brain activity alterations in SSHL using static and dynamic fractional amplitude of low-frequency fluctuation (fALFF) analysis.

Methods

Resting-state functional magnetic resonance imaging (fMRI) data were acquired

SUBMITTER: Li J 

PROVIDER: S-EPMC10500124 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature