Risk of Multiple Primary Cancers in Patients With Merkel Cell Carcinoma: A SEER-Based Analysis.

ABSTRACT:

Importance

The risk of subsequent primary cancers after a diagnosis of cutaneous Merkel cell carcinoma (MCC) is not well established.

Objective

To evaluate the risk of subsequent primary cancers after the diagnosis of a first primary cutaneous MCC.

Design, setting, and participants

This cohort study analyzed data from 17 registries of the Surveillance, Epidemiology, and End Results (SEER) Program from January 1, 2000, to December 31, 2019. In all, 6146 patients diagnosed with a first primary cutaneous MCC were identified.

Main outcomes and measures

The primary outcome was the relative and absolute risks of subsequent primary cancers after the diagnosis of a first primary MCC, which were calculated using the standardized incidence ratio (SIR; ratio of observed t

SUBMITTER: Eid E 

PROVIDER: S-EPMC10500424 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature