Abnormal temporal variability of rich-club organization in three major psychiatric conditions.

ABSTRACT:

Introduction

Convergent evidence has demonstrated a shared rich-club reorganization across multiple major psychiatric conditions. However, previous studies assessing altered functional couplings between rich-club regions have typically focused on the mean time series from entire functional magnetic resonance imaging (fMRI) scanning session, neglecting their time-varying properties.

Methods

In this study, we aim to explore the common and/or unique alterations in the temporal variability of rich-club organization among schizophrenia (SZ), bipolar disorder (BD), and attention deficit/hyperactivity disorder (ADHD). We employed a temporal rich-club (TRC) approach to quantitatively assess the propensity of well-connected nodes to form simultaneous and stable structures in a tempor

SUBMITTER: Niu M 

PROVIDER: S-EPMC10500439 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature