Coexpression Network Construction and Visualization from Transcriptomes Underlying ER Stress Responses.

ABSTRACT: Dynamic gene expression changes are primary cellular reactions in response to most stresses and developmental cues in all organisms, including plants. With the ever-decreasing cost and increasing access, high-throughput transcriptome analyses have become a significant research tool to understand a wide spectrum of complex gene regulatory mechanisms. However, it is still challenging to understand the complete picture of gene responses because of the interactive and dynamic nature of gene expression in biological networks. Coexpression network analyses followed by network mapping are being increasingly applied to overcome this challenge. In this chapter, we will introduce detailed instructions for performing a weighted coexpression network analysis (WGCNA) and network visualization using a t

SUBMITTER: Ko DK 

PROVIDER: S-EPMC10500560 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature