EGFR_cystatinC/eGFR_creatinine ratio < 0.6 in patients with SARS-CoV-2 pneumonia: a prospective cohort study.

ABSTRACT:

Background

Shrunken Pore Syndrome (SPS), defined as a reduced ratio between two estimated filtration rates (based on cystatin C and creatinine) is an increasingly recognized risk factor for long-term mortality. Although some patients with other conditions might be erroneously identified as SPS. Our aim was to bring the focus on possible pathophysiologic mechanisms influencing the ratio in the setting of SARS-CoV-2 pneumonia and acute kidney injury.

Methods

A single-centered prospective cohort study was conducted to investigate biomarkers in symptomatic COVID-19 pneumonia patients admitted to a hospital in Latvia. Nineteen biomarkers were measured in blood and three in urine samples. Associations were sought between these biomarkers, chronic diseases and the estimated GFR

SUBMITTER: Avotins L 

PROVIDER: S-EPMC10500727 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature