Association of FTO gene variant rs9939609 with polycystic ovary syndrome from Gujarat, India.

ABSTRACT:

Background

Polycystic ovary syndrome is a multifactorial endocrine disorder impacting women of reproductive age. Variations within the FTO gene have been linked to both obesity and type 2 diabetes mellitus. Given that PCOS is frequently associated with obesity and compromised glucose tolerance, we investigated the prevalence of the rs9939609 variant within the FTO gene among women diagnosed with PCOS and a control group. Our aim is to uncover potential correlations between this genetic variant, metabolic attributes, and endocrine markers within the Gujarat province of India.

Method

We enrolled a total of 114 participants, (62 individuals diagnosed with PCOS and 52 healthy controls). DNA extraction from venous blood was conducted for all participants. The rs9939609 polymorphi

SUBMITTER: Chaudhary H 

PROVIDER: S-EPMC10500741 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature