Ontology highlight
ABSTRACT:
SUBMITTER: Bae EJ
PROVIDER: S-EPMC10500805 | biostudies-literature | 2023 Sep
REPOSITORIES: biostudies-literature
Bae Eun-Jin EJ Pérez-Acuña Dayana D Rhee Ka Hyun KH Lee Seung-Jae SJ
Molecular brain 20230914 1
Parkinson's disease (PD) is characterized by a selective loss of dopaminergic neurons. While most research on PD conducted to date has focused on neurons and, to a certain extent, glia, few studies have investigated changes in oligodendroglia. Here, we investigated the heterogeneity of oligodendrocytes from PD patients compared with those of control cases by analyzing single-nuclei transcriptomes. These analyses revealed the presence of distinct oligodendrocyte populations in PD patients indicat ...[more]