Efficacy and safety of carbon ion radiotherapy for chordomas: a systematic review and meta-analysis.

ABSTRACT:

Objective

Carbon ion radiotherapy (C-ion RT) for chordomas has been gradually performed in several research centres. This study aimed to systematically review the results of clinical reports from these institutions and to evaluate the safety and efficacy of C-ion RT.

Methods

In accordance with the PRISMA guidelines and set search strategies, we searched four databases for articles from their inception to February 11, 2023. These articles were screened, and data were extracted independently by two researchers. STATA 14.0 was used for statistical analysis of survival results.

Results

A total of 942 related articles were retrieved, 11 of which were included. Regarding lesion location, 57% (n = 552) originated in the sacral region, 41% (n = 398) in the skull base, and 2%

SUBMITTER: Dong M 

PROVIDER: S-EPMC10500892 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature