Lobe-specific analysis of perioperative chemotherapy for non-small cell lung cancer patients.

ABSTRACT:

Objectives

Perioperative cisplatin-based chemotherapy decreases the risk of death over surgery alone and is a standard of care. Here, we examined perioperative chemotherapy indications for stage IB-III non-small cell lung cancer (NSCLC) patients according to lobe-specific analysis.

Methods

Resectable NSCLC patients with stage IB-III who received perioperative chemotherapy with and without radiotherapy after lung resection were identified from the SEER database. Propensity score matching (PSM) analysis was performed to reduce the inherent bias of retrospective studies. The Kaplan-Meier method and log-rank tests were used to assess the differences in overall survival (OS).

Results

The study enrolled 23,844 patients before PSM. The perioperative chemotherapy group had be

SUBMITTER: Lei X 

PROVIDER: S-EPMC10501251 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature