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From past to present: Exploring COVID-19 in Qatar's hemodialysis population across Omicron dominant and pre-Omicron periods.

ABSTRACT: COVID-19 carries a high risk of morbidity and mortality in dialysis patients. Multiple SARS-CoV-2 variants have been identified since the start of the COVID-19 pandemic. The current study aimed to compare the incidence and outcomes of the COVID-19 Omicron dominant period versus other pre-Omicron period in hemodialysis patients. In this observational, analytical, retrospective, nationwide study, we reviewed adult chronic hemodialysis patients between March 1, 2020, and January 31, 2022. Four hundred twenty-one patients had COVID-19 during the study period. The incidence of COVID-19 due to the Omicron dominant period was significantly higher than other pre-Omicron period (30.3% vs. 18.7%, P<0.001). In contrast, the admission rate to ICU was significantly lower in the Omicron dominant period than in the pre-Omicron period (2.8% vs. 25%, P<0001) but with no significant difference in ICU length of stay. The mortality rate was lower in the Omicron dominant period compared to the pre-Omicron period (2.4% vs. 15.5%, P<0.001). Using multivariate analysis, older age [OR 1.093 (95% CI 1.044-1.145); P<0.0001] and need for mechanical ventilation [OR 70.4 (95% CI 20.39-243.1); P<0.0001] were identified as two independent risk factors for death in hemodialysis patients with COVID-19. In Conclusion, the COVID-19 Omicron variant had a higher incidence and lower morbidity and mortality than pre-Omicron period in our hemodialysis population.

SUBMITTER: Hamad A

PROVIDER: S-EPMC10501587 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature

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From past to present: Exploring COVID-19 in Qatar's hemodialysis population across Omicron dominant and pre-Omicron periods.

Hamad Abdullah A Elgaali Musab M Ghonimi Tarek T Elshirbeny Mostafa M Ali Mohamed M Ibrahim Rania R Othman Muftah M Abuhelaiqa Essa E Ezzat Hany H Boubaker Karima K Alkadi Mohamad M Al-Malki Hassan H

PloS one 20230914 9

COVID-19 carries a high risk of morbidity and mortality in dialysis patients. Multiple SARS-CoV-2 variants have been identified since the start of the COVID-19 pandemic. The current study aimed to compare the incidence and outcomes of the COVID-19 Omicron dominant period versus other pre-Omicron period in hemodialysis patients. In this observational, analytical, retrospective, nationwide study, we reviewed adult chronic hemodialysis patients between March 1, 2020, and January 31, 2022. Four hund ...[more]

PMID: 37708230

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Project description:BackgroundCannabis sativa L. (Cannabaceae) has been widely used by humans throughout its history for a variety of purposes (medicinal, alimentary and other uses). Armenia, with its rich cultural history and diverse ecosystems, offers a unique context for ethnobotanical research about traditional uses of Cannabis. The present work aims to study and preserve the local traditional knowledge about Cannabis in Armenia by conducting interviews with informants and through a literature review.MethodsThe first part of the dataset was gathered with ethnobotanical surveys, through questionnaires conducted with 27 informants. The second part of the data was obtained from a comprehensive bibliographic search in English, Armenian and Russian language. Since the data acquisition was different, the quantitative analyses (calculation of the number of use reports and percentages) were performed separately.ResultsDuring the interviews 52 use reports and 3 vernacular names were recorded, while the bibliographic data from 20 references, provided us with 56 use reports and 17 Cannabis vernacular names, from the 5th century to 2020. Our results indicate that medicinal applications, particularly for human ailments, and fibre use have markedly dwindled, contrasting with earlier epochs. However, the Cannabis seeds continue to be consumed in celebrative and symbolic dishes such as aghandz and tolma.ConclusionsThe recent decline in the medicinal use of Cannabis contrasts with earlier periods when access to pharmacological remedies was limited, and societal views of the plant were more positive. This shift can be partly attributed to the impact of legal restrictions. In contrast, the use of Cannabis seeds for alimentary purposed is importantly maintained nowadays. As medicinal use, fibre use has also declined, largely due to the availability of more competitive modern products. The loss of vernacular names over time, as detected in this study, also reflects the erosion of traditional knowledge, which correlates with diminishing use. Despite the small sample size and limited geographic scope, the combination of two approaches-information from contemporary informants and a systematic bibliographic review-has provided valuable insights into the changes in the traditional use of Cannabis in Armenia, that has not been explored in this way before.

Dataset Information

From past to present: Exploring COVID-19 in Qatar's hemodialysis population across Omicron dominant and pre-Omicron periods.

Publications

From past to present: Exploring COVID-19 in Qatar's hemodialysis population across Omicron dominant and pre-Omicron periods.

Similar Datasets

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